解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The cytotoxicity and immunosuppressive activities of jaborosalactone-L and three 16 alpha-oxygenated withanolides from the leaves of Discopodium penninervium were studied. Jaborosalactone-L showed cytotoxicity only to the murine macrophage cell line, RAW 264.7, but the 16 alpha-oxygenated withanolides exhibited cytoto...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957594
更新日期:1997-02-01 00:00:00
abstract::An isolated rabbit heart Langendorff preparation paced electrically was used to evaluate the effects of a highly purified, high molecular weight fraction of oligomeric procyanidines isolated from Vitis vinifera seeds on myocardial reperfusion injury after 40 minutes of low flow (1 ml/min) ischemia. Infusion of the hea...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957956
更新日期:1996-12-01 00:00:00
abstract::A novel stilbene glucoside was isolated from the root bark of Morus alba L. (Moraceae), along with mulberroside A, cis-mulberroside A, oxyresveratrol. The structure of the novel stilbene glucoside was determined as oxyresveratrol 3'-O-beta-glucopyranoside. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957972
更新日期:1996-12-01 00:00:00
abstract::Paeoniae Radix (the roots of Paeonia lactiflora Pallas) is a crude drug that is used in Asia and Europe to improve blood flow. We studied its vasodilator effect and mechanisms of action in vitro. The extract from Paeoniae Radix (PRE) relaxed prostaglandin F2a-precontracted aortic ring preparations of isolated rat aort...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957934
更新日期:1996-10-01 00:00:00
abstract::The benzophenanthridine alkaloids sanguinarine and chelerythrine of Chelidonium majus, L. (Papaveraceae), are potent inhibitors of 5-lipoxygenase in polymorphonuclear leukocytes and 12-lipoxygenase in mouse epidermis, while the activity of soybean lipoxygenase is not influenced. The extract of the herb of Ch.majus als...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957924
更新日期:1996-10-01 00:00:00
abstract::Isoplexis is a plant genus closely related to Digitalis. Members of this genus contain cardenolides considered more "primitive" than those present in Digitalis. Isoplexis plants, tissue cultures, and isolated cardenolides may thus be used to elucidate the biosynthesis of cardenolides in the Scrophulariaceae. Therefore...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957937
更新日期:1996-10-01 00:00:00
abstract::From the methanolic extract of the whole plants of Bidens pilosa the new beta-D-glucopyranosyloxy-3-hydroxy-6(E)-tetradecen-8, 10,12-triyne besides a known polyine has been isolated and identified mainly by IR and NMR methods. The new compound showed overgrowing action against normal and transformed human cell lines i...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957902
更新日期:1996-08-01 00:00:00
abstract::An antimicrobial diterpene was isolated from Alpinia galanga in the screening for potentiators of phytochemical antibiotic action. The structure was elucidated by spectral data and identified as (E)-8 beta, 17-epoxylabd-12-ene-15, 16-dial (1). Diterpene 1 synergistically enhanced the antifungal activity of quercetin a...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957890
更新日期:1996-08-01 00:00:00
abstract::Solasodine--a steroid present in the mucilaginous exotesta of the seed in Solanum viarum Dunal (syn. S. khasianum var. chatterjeeanum) is a major source of steroidal raw material. Evidence for the site of solasodine synthesis was sought through reciprocal grafts involving steroid-bearing S. viarum (both diploid and au...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957905
更新日期:1996-08-01 00:00:00
abstract::Soybean saponin is one of several soybean glycosides. Recently, new soybean saponins which possess the DDMP (2,5-dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one) moiety have been detected. Soyasaponin beta g of these new soybean saponins was shown to inhibit hydrogen peroxide damage to mouse fibroblast cells. Not only t...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957871
更新日期:1996-06-01 00:00:00
abstract::Natural products research is increasingly turning to marine animals, plants, and microbes as source organisms. Several marine natural products are currently in preclinical and clinical evaluation, others show promising biological activities in in vitro and in vivo assays. Investigations of biological and chemical ecol...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2006-957861
更新日期:1996-06-01 00:00:00
abstract::Bioassay-directed fractionation of the chloroform-methanol (1:1) extract of Dodonaea viscosa (L.) Jacq. (Sapindaceae) resulted in the isolation of four active spasmolytic principles: sakuranetin (1), 6-hydroxykaempferyl 3,7-dimethyl ether (2) hautrivaic acid (3), and ent-15, 16-epoxy-9 alpha H-labda-13(16)14-diene-3 b...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957840
更新日期:1996-04-01 00:00:00
abstract::The configurations of the component amino acids in ginseng tetrapeptide 1 isolated from Panax ginseng were determined by HPLC with an optical resolution column and the structure of 1 was established to be H-L-Val-gamma-D-Glu-D-Arg- Gly-OH. Synthesis of the ginseng tetrapeptide, 1, and of the configuration and conjugat...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957830
更新日期:1996-04-01 00:00:00
abstract::Characterization of an alkali-soluble isolate from Pinus nigra Arnold (Pinaceae) seed cones by thioacidolysis revealed a significant phenylpropanoid (i.c. lignin) component which may provide the observed anti-HIV-1 activity for this substance. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957801
更新日期:1996-02-01 00:00:00
abstract::The 80% and 70% acetone extracts from fruits and leaves of Crataegus sinaica Boiss (Rosaceae) and the ethyl acetate-, butanol-, and water-fractions obtained from these initial extracts as well as the isolated compounds, quercetin (1) (1), hyperoside (quercetin 3-O-galactoside) (2) (2), rutin (quercetin 3-O-rutinoside)...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957786
更新日期:1996-02-01 00:00:00
abstract::Vitex agnus-castus, the chaste tree, is used against disorders of the female sexual organs and as an anaphrodisiac. Active constituents are not known. In this study the essential oil of the fruits was investigated by GC and GC-MS. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957814
更新日期:1996-02-01 00:00:00
abstract::Bioassay-guided fractionation of an MeCOEt extract of Frullania nisquallensis Sull. has furnished a DNA-damaging sesquiterpene, costunolide (1), and two inactive compounds, a sesquiterpene (-)-frullanolide (2) and a tridepside tenuiorin (3). (13)C-NMR data of 3 are reported. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957800
更新日期:1996-02-01 00:00:00
abstract::Two new secodammarane triterpenoid saponins were isolated from the leaves of Cyclocarya paliurus. Based on chemical and spectral analysis they were assigned as (20S)-20-hydroxy-24-O-alpha-L-arabino-pyranosyl-3,4- secodammar-4(28),11,25-trien-3-oic acid, named cyclocarioside II and 25-hydroxy-(20S,24R)-epoxy-12R-O-beta...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959369
更新日期:1995-12-01 00:00:00
abstract::Bisbenzylisoquinoline alkaloids are known to affect immune responses as well as inflammatory responses, and have been used for the treatment of inflammatory symptoms in China. This study is aimed at elucidating the inhibitory effects of two alkaloids, fangchinoline and isotetrandrine, on the induction of the proinflam...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959356
更新日期:1995-12-01 00:00:00
abstract::From the bulbs of Vietnamese Hippeastrum equestre Herb. (Amaryllidaceae), besides the well known alkaloids lycorine, tazettine, and hippeastrine, a new alkaloid, phamine, has been isolated. Its structure was established by spectroscopic methods. ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-959375
更新日期:1995-12-01 00:00:00
abstract::A total of 37 commercial samples of Ginseng Radix, the origins of which belonged to Panax ginseng C. A. Meyer, P. quinquefolia Linn. (American ginseng), and P. notoginseng Burkill (sanchi-ginseng), respectively, were collected from the Taiwan herbal markets. The contents of nine ginsenosides, Rb(1), Rb(2), Rc, Rd, Re,...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958137
更新日期:1995-10-01 00:00:00
abstract::The crude ethanol extract from the leaves of Dendropanax arboreus (Araliaceae) from Monteverde, Costa Rica, exhibits cytotoxic activity against Hep-G2, A-431, H-4IIE, and L-1210 tumor cell lines, but is not toxic against normal hepatocytes. The active component has been isolated by activity-directed separation and ide...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958139
更新日期:1995-10-01 00:00:00
abstract::Examined in vitro were the effects of some triterpenoids from Panax (Araliaceae) and Glycyrrhiza (Leguminosae) spp. on the sensitivity to daunomycin (DAU) and vinblastine (VBL) of adriamycin (ADM)-resistant P388 leukemia cells (P388/ADM), which were resistant to multiple anticancer drugs. Quasipanaxatriol, 20(S)-proto...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958126
更新日期:1995-10-01 00:00:00
abstract::Three pyrrolizidine alkaloids were isolated from Eupatorium portoricense and their structures elucidated by spectroscopic methods as (-)-viridifloryl-supinidine (amabiline), (-)-viridifloryl-heliotridine (echinatine), and C12- O-acetyl-(-)-viridifloryl-heliotridine (O(12)-acetylechinatine). ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958112
更新日期:1995-08-01 00:00:00
abstract::Products of lipoxygenase metabolism play a role in the pathogenesis of psoriasis. Four protoberberine alkaloids, berberine, oxyberberine, jatrorrhizine, columbamine, and two aporphine alkaloids, magnoflorine, and corytuberine, isolated from Mahonia aquifolium, were tested for lipoxygenase inhibition. Oxyberberine, cor...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958107
更新日期:1995-08-01 00:00:00
abstract::Four diterpenoids, carnosic acid (1), carnosol (2), rosmanol (3), and epirosmanol (4), were isolated as antioxidative agents from the leaves of Rosmarinus officinalis by bioassay-directed fractionation. These diterpenoids inhibited superoxide anion production in the xanthine/xanthine oxidase system. Mitochondrial and ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958094
更新日期:1995-08-01 00:00:00
abstract::This paper studies the effect of different concentrations of ethephon on the levels of the sesquiterpene, nootkatone, and of the flavanones, naringin and narirutin, in grapefruit fruits. The results show that nootkatone synthesis and/or accumulation was stimulated by all the concentrations of ethephon assayed, while t...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958077
更新日期:1995-06-01 00:00:00
abstract::The concentrations of taxol and related compounds in the bark and needles of Taxus cuspidata grown on Mt. Jiri, Mt. Sobaek, and Cheju Island, and T. cuspidata var. latifolia on Ullung Island in Korea were determined by high performance liquid chromatography (HPLC). The taxane content significantly varied with the loca...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958069
更新日期:1995-06-01 00:00:00
abstract::The antisecretory activity of Guazuma ulmifolia bark was examined in rabbit distal colon mounted in an Ussing chamber. Chloride secretion was stimulated by cholera toxin and prostaglandin E2 (PGE2). Guazuma ulmifolia extract (GUE) completely inhibited cholera toxin-induced secretion if the extract was added to the muc...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958057
更新日期:1995-06-01 00:00:00
abstract::A known sesquiterpene lactone, encelin, isolated from the Mexican species Montanoa speciosa (Compositae), was assayed for biocidal activity on fungal cells of Mucor rouxii. The results indicate that encelin has a determining action on growth and the morphogenetic process of fungal cells. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958046
更新日期:1995-04-01 00:00:00
abstract::The effect of a lignan-enriched extract of the fruits of Schisandra chinensis (FS) on hepatic glutathione (GSH) status was examined in both control and carbon tetrachloride (CCl4)-treated rats. FS treatment caused a dose-dependent enhancement in hepatic GSH status, as evidenced by significant increases in hepatic GSH ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958032
更新日期:1995-04-01 00:00:00
abstract::Cuttings of a clone of A. annua L. (Asteraceae), grown under 16 h photoperiod for 55 days were transferred to six photoperiod treatments in the greenhouse. Under short photoperiods (8, 10, or 12 h), plants flowered after two weeks; plants under long photoperiods (16, 20, or 24 h) remained vegetative until termination ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-958040
更新日期:1995-04-01 00:00:00
abstract::25 Amaryllidaceae alkaloids belonging to different skeletal types were evaluated for their cytotoxic activity against one murine non-tumoral cell line (LMTK) and two human tumoral cell lines (Molt4 and HepG2) according to established protocols. Significant differences of activity related with the type of skeleton of t...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958007
更新日期:1995-02-01 00:00:00
abstract::The oligomeric stilbenes (+)-alpha-viniferin (1), miyabenol C (2), and kobophenol A (3) have been isolated from Caragana sinica (Buchoz) Rehd (Leguminosae). (+)-alpha-Viniferin (1) and miyabenol C (2) exhibited protein kinase C inhibitory activity at low micromolar concentrations. (+)-alpha-Viniferin inhibited keratin...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957996
更新日期:1995-02-01 00:00:00
abstract::The traditional analgesic and antipyretic Ethiopian drug "Dingetegna" is made of dried root material of Taverniera abyssinica A. Rich (Leguminosae). In a screening for nematicidal natural products, "Dingetegna" extracts showed strong nematicidal activities towards C. elegans. In the following, medicarpin and 4-hydroxy...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959569
更新日期:1994-12-01 00:00:00
abstract::Two diterpenoids were prepared from hexane anti-inflammatory extracts of the Spanish herb Sideritis javalambrensis: ent-13-epi-12 alpha-acetoxymanoyl oxide (= "manoyl oxide F1") and ent-8 alpha-hydroxy-labda-13(16), 14-diene (= "labdane F2"). They were evaluated for possible anti-inflammatory actions in vitro in the c...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959559
更新日期:1994-12-01 00:00:00
abstract::Anti-sera against a complement-activating pectin (AR-2IIb), which was purified from the roots of Angelica acutiloba Kitagawa, were obtained by immunization of rabbits, and a polyclonal anti-AR-2IIb antibody of the IgG class was purified by affinity chromatography on AR-2IIb-immobilized Sepharose and Protein G-Sepharos...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959524
更新日期:1994-10-01 00:00:00
abstract::In the extremely skin irritant and caustic latex of Excoecaria agallocha the major part of the polyfunctional diterpene esters (DTE) (group I) are aliphatic polyunsaturated 9,13,14-orthoesters of the daphnane-type parent alcohol 5 beta-hydroxyresiniferonol-6 alpha, 7 alpha-epoxide, esterified simultaneously in their 2...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959499
更新日期:1994-08-01 00:00:00
abstract::Acetonylgeraniin, an active principle isolated from the seeds of Euphoria longana Lam. (Sapindaceae), reversed the fall in arterial blood pressure in conscious hypertensive rats (SHRs) with orthostatic hypotension induced by injection of hexamethonium into animals subjected to 90 degrees head-up tilts for 60 seconds. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959487
更新日期:1994-08-01 00:00:00
abstract::Several procyanidin dimers and an epicatechin trimer purified from Douglas fir bark tannins were compared with their monomer components (+)-catechin and (-)-epicatechin for their abilities to inhibit the biochemical effects of the potent tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA) in mouse epidermis in v...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959466
更新日期:1994-06-01 00:00:00